warning 59 countries ICD-10 B04

Monkeypox

Monkeypox clinical and global spread profile: 59 countries, 81 WHO outbreak events since 1997.

Monkeypox · ICD-10 B04 · ICD-11 1E71 · 81 WHO events across 59 countries (1997–2026).

Top affected countries

Country Region Events % of global
Congo Democratic Republic of the AFR 6 7%
United Kingdom of Great Britain and Northern Ireland EUR 3 4%
South Africa AFR 3 4%
Nigeria AFR 3 4%
Lebanon EMR 2 2%
Singapore WPR 2 2%
Uganda AFR 2 2%
Kenya AFR 2 2%
Greece EUR 2 2%
United States of America AMR 2 2%
Congo AFR 2 2%
Central African Republic AFR 2 2%
Rwanda AFR 2 2%
Cameroon AFR 2 2%
Burundi AFR 2 2%

Distribution by WHO region

Region Events Share
AFR 34 42%
EUR 23 28%
EMR 7 9%
WPR 7 9%
AMR 6 7%
SEAR 2 2%
Unassigned 2 2%

Annual outbreak timeline

Year Events Countries
2026 2 2
2025 35 35
2024 8 8
2023 1 1
2022 26 26
2021 2 2
2020 1 1
2019 1 1
2018 2 2
2017 1 1
2016 1 1
1997 1 1

Peak year: 2025 (35 events).

Decade summary

Decade Events
1990s 1
2010s 5
2020s 75

WHO case definition

A disease caused by an infection with monkeypox virus. In the first phase, this disease is characterised by lymphadenopathy, fever, headache, or malaise

Countries Affected

59

Outbreak Events

81

Year Range

1997–2026

coronavirus

ICD-10 B04

Monkeypox

Visualization

Global Prevalence Snapshot

Based on WHO Disease Outbreak News events (1997–2026).

81 Outbreak events · Emerging / Moderate

Risk Level

Endemic / High Risk
Emerging / Moderate
Sporadic / Low Risk