warning 3 events B00-B09 • AFR

Monkeypox in South Africa

Monkeypox has 3 WHO-tracked outbreak events in South Africa between 2022 and 2025.

Monkeypox · South Africa · 3 WHO events across 3 calendar years (2022–2025).

Event log

Year DON ID ICD-10 ICD-11
2025 DON2936 B04 1E71
2024 DON2877 B04 1E71
2022 DON2752 B04 1E71

Annual cadence

Year Events
2025 1
2024 1
2022 1

Most active year: 2025 with 1 event.
Quiet years with no events: 1.

Position within the disease

  • South Africa is rank #4 of 59 for this disease.
  • The country sits in the WHO AFR region.
  • Last reported event: 2025 (1 year ago).

Regional peers (AFR)

18 countries in this region report this disease. Median event count: 2.

Country Events
Congo Democratic Republic of the 6
Nigeria 3
South Africa 3
Kenya 2
Congo 2
Rwanda 2
Uganda 2
Central African Republic 2

How this disease ranks among South Africa’s threats

Monkeypox is rank #2 of 12 diseases reported by South Africa to the WHO. The full country profile is at the South Africa Hub.

Outbreak Events

3

First Reported

2022

Latest Reported

2025

Flag of South Africa

Country

South Africa • AFR